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Creators/Authors contains: "Weires, Nicholas A."

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  1. ; ; (, Journal of the American Chemical Society)
    Full Text Available 
  2. ; ; (, Angewandte Chemie International Edition)
    Abstract An alkoxycarbonyl radical cyclization–cross‐coupling cascade has been developed that allows functionalized γ‐butyrolactones to be prepared in one step from simple tertiary alcohol‐derived homoallylic oxalate precursors. The reaction succeeds with aryl and vinyl electrophiles and is compatible with heterocyclic fragments in both coupling partners. This chemistry allows for the rapid construction of spirolactones, which are of interest in drug discovery endeavors. 
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